Maternal high-fat diet is associated with impaired fetal lung development
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چکیده
منابع مشابه
Maternal high-fat diet is associated with impaired fetal lung development.
Maternal nutrition has a profound long-term impact on infant health. Poor maternal nutrition influences placental development and fetal growth, resulting in low birth weight, which is strongly associated with the risk of developing chronic diseases, including heart disease, hypertension, asthma, and type 2 diabetes, later in life. Few studies have delineated the mechanisms by which maternal nut...
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Reina S. Mayor, Katelyn E. Finch, Jordan Zehr, Eugenia Morselli, Michael D. Neinast, Aaron P. Frank, Lisa D. Hahner, Jason Wang, Dinesh Rakheja, Biff F. Palmer, Charles R. Rosenfeld, Rashmin C. Savani, and Deborah J. Clegg Center for Pulmonary and Vascular Biology and Division of Neonatal-Perinatal Medicine, Department of Pediatrics, University of Texas Southwestern Medical Center, Dallas, Texa...
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OBJECTIVE Recent evidence indicates that the adult hematopoietic system is susceptible to diet-induced lineage skewing. It is not known whether the developing hematopoietic system is subject to metabolic programming via in utero high-fat diet (HFD) exposure, an established mechanism of adult disease in several organ systems. We previously reported substantial losses in offspring liver size with...
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To begin to understand the contributions of maternal obesity and over-nutrition to human development and the early origins of obesity, we utilized a non-human primate model to investigate the effects of maternal high-fat feeding and obesity on breast milk, maternal and fetal plasma fatty acid composition and fetal hepatic development. While the high-fat diet (HFD) contained equivalent levels of...
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OBJECTIVE Non-alcoholic fatty liver disease (NAFLD) is an important co-morbidity associated with obesity and a precursor to steatohepatitis. However, the contributions of gestational and early life influences on development of NAFLD and NASH remain poorly appreciated. METHODS Two independent studies were performed to examine whether maternal over-nutrition via exposure to high fat diet (HFD) ...
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ژورنال
عنوان ژورنال: American Journal of Physiology-Lung Cellular and Molecular Physiology
سال: 2015
ISSN: 1040-0605,1522-1504
DOI: 10.1152/ajplung.00105.2015